Abstract
The authors report the treatment results of 89 children with renal tumors (excluding carcinoma) seen from 1988 to 1992, 71 (79.8%) with favorable-histology Wilms' tumor (survival 86%) and 18 (20.2%) with unfavorable histology, including anaplastic nephroblastoma, clear-cell sarcoma, and rhabdoid tumor (survival 61%). Preoperative chemotherapy (ChT) was given to 46 patients (survival 84%); none was given to 43 with either tumors in the 1st year of life, massive hematuria, or tumor growth during ChT (survival 78%). There were 3 tumor ruptures in the latter group compared to 1 in the former group.
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d'Angio GJ (1983) SIOP and the Management of Wilms' tumor. J Clin Oncol 10: 595
d'Angio GJ, Breslow N, Beckwith JB, et al (1989) Treatment of Wilms tumor. Results of the third National Wilms' Tumor Study. Cancer 69: 349–360
Beckwith JB (1983) Wilms' tumor and other renal tumors of childhood: a selective review from the National Wilms' Tumor Study Pathology Center. Hum Pathol 14: 481–492
Beckwith JB (1986) Wilms' tumor and other renal tumors of childhood. An update. J Urol 136: 320
Beckwith JB (1993) The impact of tumor histology on treatment and prognosis of pediatric neoplasms. Semin Pediatr Surg 1: 11–18
Bonadio JF, Storer B, Norkool P, et al (1985) Anaplastic Wilms' tumor: clinical and pathologic studies. J Clin Oncol 3: 513–520
Breslow N, Churchill G, Nernith B, et al (1986) Clinicopathologic features and prognosis for Wilms' tumor patients with metastases at diagnosis. Cancer 58: 2501–2511
Breslow N, Palmer N, Hill L, et al (1978) Wilms' tumor. Prognostic factors for patients without metastases at diagnosis. Cancer 41: 1577–1589
Farewell VT, d'Angio GJ, Breslow N, Norhool P (1981) Retrospective validation of new staging system for Wilms' tumor. Cancer Clin Trials 4: 167–171
Gearhart JP, Partin AWE, Leventhal B, et al (1992) The use of nuclear morphometry to predict response to therapy in Wilms' tumor. Cancer 69: 804–808
Greenberg M. Burnweit C, Filler R, et al (1991) Preoperative chemotherapy for children with Wilms tumor. J Pediatr Surg 8: 949–956
Haas JE, Bonadio JF, Beckwith JB (1984) Clear cell sarcoma of the kidney with emphasis on ultrastructural studies. Cancer 54: 2978–2987
Kofous A, Hansen MF, Lampkin BC, et al (1984) Loss of alleles at loci on human chromosome II during genesis of Wilms' tumor locus. Nature 309: 170–172
Ladd WE (1938) Embryoma of kidney (Wilms' tumor). Ann Surg 108: 885–902
Lemerle J, Vaute PA, Tournade MF, et al (1983) Effectiveness of preoperative chemotherapy in Wilms' tumor: results of an International Society of Paediatric Oncology (SIOP) clinical trial. J Clin Oncol 1: 604–609
Shochat SJ (1993) Wilms' tumor. Diagnosis and treatment in the 1990s. Semin Pediatr Surg 1: 60
Wammack R, Fisch M, Spaar HJ, et al (1992) Wilms' tumor — treatment and prognosis of 373 children. World J Urol 10: 100–106
Weeks DA, Beckwith JB, Mieran GW, Luckey DW (1989) Rhabdoid tumor of kidney: a report of 111 cases from the National Wilms' Tumor Study Pathology Center. Am J Surg Pathol 13: 439–458
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Pýcha, K., Šnajdauf, J., Koutecký, J. et al. Surgical tactics in the treatment of malignant renal tumors in childhood. Pediatr Surg Int 12, 145–147 (1997). https://doi.org/10.1007/BF01349984
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DOI: https://doi.org/10.1007/BF01349984