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Primary small cell carcinoma of the esophagus with ectopic gastrin production

Report of a case and review of the literature

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Summary

A case of primary small cell carcinoma of the esophagus in which extensive hormonal studies could be performed is reported. The tumor was considered as a neuroendocrine tumor because the tumor cells showed intracytoplasmic argyrophilia, neurosecretory granules, and positive stain for neuron-specific enolase with Grimelius stain, electron microscopy, and immunohistochemistry, respectively. Furthermore, the tumor was regarded as a gastrin-producing tumor because of positive stain for gastrin in the tumor cells. The present case is the esophagus with ectopic gastrin production.

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Authors and Affiliations

  1. Second Department of Pathology, Niigata University School of Medicine, Niigata, Japan

    Tadashi Nishimaki MD, Tsutomu Suzuki MD, Takeaki Fukuda MD, Kikuo Aizawa MD, Otsuo Tanaka MD & Terukazu Muto MD

  2. First Department of Surgery, Niigata University School of Medicine, 1-757 sahimachi-dori, 951, Niigata, Japan

    Tadashi Nishimaki MD, Tsutomu Suzuki MD, Takeaki Fukuda MD, Kikuo Aizawa MD, Otsuo Tanaka MD & Terukazu Muto MD

Authors
  1. Tadashi Nishimaki MD
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  2. Tsutomu Suzuki MD
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  3. Takeaki Fukuda MD
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  4. Kikuo Aizawa MD
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  5. Otsuo Tanaka MD
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  6. Terukazu Muto MD
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Nishimaki, T., Suzuki, T., Fukuda, T. et al. Primary small cell carcinoma of the esophagus with ectopic gastrin production. Digest Dis Sci 38, 767–771 (1993). https://doi.org/10.1007/BF01316813

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  • DOI: https://doi.org/10.1007/BF01316813

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