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Effect of inactivator(s) formed from copper and phenol impurity(ies) on the sedimentation rate of transfective poliovirion RNA

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Summary

Transfective poliovirion RNA after inactivation by the inactivator or inactivators formed from copper and an impurity or impurities in reagent-grade phenol sediments more heterogeneously and, on the average, more slowly than intact transfective RNA. The data are consistent with the hypothesis that the inactivator causes scission of the viral RNA molecules.

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References

  1. Dubes, G. R., Wegrzyn, R. J., Masoud, A. N.: Inactivation of transfective poliovirion RNA by a product or products of the interaction of trace copper with an impurity or impurities in reagent-grade phenol. Arch. Virol.66, 27–44 (1980).

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  2. Douglas, J. D., Vasington, P. J., Noel, J. K.: Viral spectrum of an established chimpanzee liver cell line. Proc. Soc. exp. Biol. (N.Y.)121, 824–829 (1966).

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Author notes

  1. M. I. Al-Moslih

    Present address: Department of Microbiology, University of Baghdad College of Medicine, Baghdad, Iraq

Authors and Affiliations

  1. Department of Medical Microbiology, University of Nebraska College of Medicine, Omaha, Nebraska, USA

    G. R. Dubes & M. I. Al-Moslih

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  1. G. R. Dubes
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  2. M. I. Al-Moslih
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Dubes, G.R., Al-Moslih, M.I. Effect of inactivator(s) formed from copper and phenol impurity(ies) on the sedimentation rate of transfective poliovirion RNA. Archives of Virology 66, 45–51 (1980). https://doi.org/10.1007/BF01315043

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  • DOI: https://doi.org/10.1007/BF01315043

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