Skip to main content
Log in

Effect of fasting and parenteral alimentation on PIPIDA scintigraphy

  • Original Articles
  • Published:
Digestive Diseases and Sciences Aims and scope Submit manuscript

Abstract

Ten patients were prospectively studied using99mTc-PIPIDA imaging to evaluate the effects of fasting and parenteral alimentation on gallbladder function. Three of ten patients had initial nonvisualization of the gallbladder for up to 2 hr, yet had normal visualization on repeat imaging performed after resumption of oral intake or after parenteral alimentation was discontinued.99mTc-PIPIDA imaging should be interpreted with caution in patients fitting into either of these groups.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Harvey E, Loberg M, Cooper M: Tc-99m-HIDA: A new radiopharmaceutical for hepato-biliary imaging. J Nucl Med 16:533A, 1975

    Google Scholar 

  2. Loberg M, Cooper M, Harvey E, Callery P, Faith W: Development of new radiopharmaceuticals based onN-substitution of iminodiacetic acid. J Nucl Med 17:633–638, 1976

    Google Scholar 

  3. Weissmann H, Frank M, Bernstein L, Freeman L: Rapid and accurate diagnosis of acute cholecystitis with 99m-Tc-HIDA cholescintigraphy. Am J Radiol 132:523–528, 1979

    Google Scholar 

  4. Szlabick R, Catto J, Fink-Bennett D, Ventura V: Hepatobiliary scanning in the diagnosis of acute cholecystitis. Arch Surg 115:540–544, 1980

    Google Scholar 

  5. Shuman W, Gibbs P, Rudd T, Mack L: PIPIDA scintigraphy for cholecystitis: False positives in alcoholism and total parenteral nutrition. Am J Radiol 138:1–5, 1982

    Google Scholar 

  6. Edlund G, Kempi V, van der Linden W: Transient nonvisualization of the gallbladder by Tc-99m-HIDA cholescintigraphy in acute pancreatitis: Concise communication. J Nucl Med 23:117–120, 1982

    Google Scholar 

  7. Freitas J, Fink-Bennet D, Thrall J, Resinger W, Calderon H, Mirkes S, Shah P: Efficacy of hepatobiliary imaging in acute abdominal pain: Concise communication. J Nucl Med 21:919–924, 1980

    Google Scholar 

  8. Fonseca C, Greenberg D, Rosenthall L, Arzoumanian A, Lisbona R: 99m-Tc-IDA in the differential diagnosis of acute cholecystitis and acute pancreatitis. Radiology 130:525–527, 1979

    Google Scholar 

  9. Roller R, Mallory A, Caruthers SB Jr, Schaefer J: Oral cholecystography after alcoholic pancreatitis. Gastroenterology 73:218–220, 1977

    Google Scholar 

  10. Lindor K, Fleming CR, Abrams A, Hirschkorn M: Liver function values in adults receiving total parenteral nutrition. JAMA 241:2398–2400, 1979

    Google Scholar 

  11. Rowlands B, MacFayden B, DeJong P, Dudrick S: Monitoring hepatic dysfunction during intravenous hyperalimentation. J Surg Res 28:471–478, 1980

    Google Scholar 

  12. Roslyn J, Pitt H, Mann L, Ament M, DenBesten L: Long-term total parenteral nutrition induces gallbladder disease. Gastroenterology 80:1264A, 1980

    Google Scholar 

  13. Hamilton R, Davis WC, Stephenson D, Magee D: Effects of parenteral hyperalimentation on upper gastrointestinal secretions. Arch Surg 102:348–352, 1971

    Google Scholar 

  14. Williams CN, Morse J, Macdonald I, Kotoor R, Riding M: Increased lithogenicity of bile on fasting in normal subjects. Am J Dig Dis 22:189–194, 1977

    Google Scholar 

  15. Bloch H, Thornton J, Heaton K: Effects of fasting on the composition of gallbladder bile. Gut 21:1087–1089, 1980

    Google Scholar 

  16. Duane WC, Ginsberg R, Bennion L: Effects of fasting on bile acid metabolism and biliary lipid composition in man. J Lipid Res 17:211–219, 1976

    Google Scholar 

  17. O'Brien J, Shaffer E, Williams LF Jr, Small D, Lyun J, Wittenberg J: A physiological model to study gallbladder function in primates. Gastroenterology 67:119–125, 1974

    Google Scholar 

  18. Van Berge Henegouwen G, Hofmann A: Nocturnal gallbladder storage and emptying in gallstone patients and healthy subjects. Gastroenterology 75:879–885, 1978

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Potter, T., McClain, C.J. & Shafer, R.B. Effect of fasting and parenteral alimentation on PIPIDA scintigraphy. Digest Dis Sci 28, 687–691 (1983). https://doi.org/10.1007/BF01312557

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01312557

Keywords

Navigation