Abstract
Ten patients were prospectively studied using99mTc-PIPIDA imaging to evaluate the effects of fasting and parenteral alimentation on gallbladder function. Three of ten patients had initial nonvisualization of the gallbladder for up to 2 hr, yet had normal visualization on repeat imaging performed after resumption of oral intake or after parenteral alimentation was discontinued.99mTc-PIPIDA imaging should be interpreted with caution in patients fitting into either of these groups.
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Harvey E, Loberg M, Cooper M: Tc-99m-HIDA: A new radiopharmaceutical for hepato-biliary imaging. J Nucl Med 16:533A, 1975
Loberg M, Cooper M, Harvey E, Callery P, Faith W: Development of new radiopharmaceuticals based onN-substitution of iminodiacetic acid. J Nucl Med 17:633–638, 1976
Weissmann H, Frank M, Bernstein L, Freeman L: Rapid and accurate diagnosis of acute cholecystitis with 99m-Tc-HIDA cholescintigraphy. Am J Radiol 132:523–528, 1979
Szlabick R, Catto J, Fink-Bennett D, Ventura V: Hepatobiliary scanning in the diagnosis of acute cholecystitis. Arch Surg 115:540–544, 1980
Shuman W, Gibbs P, Rudd T, Mack L: PIPIDA scintigraphy for cholecystitis: False positives in alcoholism and total parenteral nutrition. Am J Radiol 138:1–5, 1982
Edlund G, Kempi V, van der Linden W: Transient nonvisualization of the gallbladder by Tc-99m-HIDA cholescintigraphy in acute pancreatitis: Concise communication. J Nucl Med 23:117–120, 1982
Freitas J, Fink-Bennet D, Thrall J, Resinger W, Calderon H, Mirkes S, Shah P: Efficacy of hepatobiliary imaging in acute abdominal pain: Concise communication. J Nucl Med 21:919–924, 1980
Fonseca C, Greenberg D, Rosenthall L, Arzoumanian A, Lisbona R: 99m-Tc-IDA in the differential diagnosis of acute cholecystitis and acute pancreatitis. Radiology 130:525–527, 1979
Roller R, Mallory A, Caruthers SB Jr, Schaefer J: Oral cholecystography after alcoholic pancreatitis. Gastroenterology 73:218–220, 1977
Lindor K, Fleming CR, Abrams A, Hirschkorn M: Liver function values in adults receiving total parenteral nutrition. JAMA 241:2398–2400, 1979
Rowlands B, MacFayden B, DeJong P, Dudrick S: Monitoring hepatic dysfunction during intravenous hyperalimentation. J Surg Res 28:471–478, 1980
Roslyn J, Pitt H, Mann L, Ament M, DenBesten L: Long-term total parenteral nutrition induces gallbladder disease. Gastroenterology 80:1264A, 1980
Hamilton R, Davis WC, Stephenson D, Magee D: Effects of parenteral hyperalimentation on upper gastrointestinal secretions. Arch Surg 102:348–352, 1971
Williams CN, Morse J, Macdonald I, Kotoor R, Riding M: Increased lithogenicity of bile on fasting in normal subjects. Am J Dig Dis 22:189–194, 1977
Bloch H, Thornton J, Heaton K: Effects of fasting on the composition of gallbladder bile. Gut 21:1087–1089, 1980
Duane WC, Ginsberg R, Bennion L: Effects of fasting on bile acid metabolism and biliary lipid composition in man. J Lipid Res 17:211–219, 1976
O'Brien J, Shaffer E, Williams LF Jr, Small D, Lyun J, Wittenberg J: A physiological model to study gallbladder function in primates. Gastroenterology 67:119–125, 1974
Van Berge Henegouwen G, Hofmann A: Nocturnal gallbladder storage and emptying in gallstone patients and healthy subjects. Gastroenterology 75:879–885, 1978
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Potter, T., McClain, C.J. & Shafer, R.B. Effect of fasting and parenteral alimentation on PIPIDA scintigraphy. Digest Dis Sci 28, 687–691 (1983). https://doi.org/10.1007/BF01312557
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DOI: https://doi.org/10.1007/BF01312557