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Influence of infection with an influenza A virus (fowl plague) on Ca++-uptake and lipid metabolism of chick embryo cells in culture

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Summary

After infection of primary chick embryo cells with an influenza A virus (FPV) the synthesis of polar lipids was specifically inhibited, while mono-, di- and triacylglycerols and fatty acids accumulated. Influx of Ca++ accelerated and Ca++ accumulated in the infected cells. Since enzymes like choline phosphotransferase are sensitive to high concentrations of Ca++, specific inhibition of the synthesis of polar lipids is presumably due to an increased influx of Ca++ by the infection.

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  1. Institut für Virologie, Justus-Liebig-Universität Giessen, Giessen, Federal Republic of Germany

    K. W. Frischholz & C. Scholtissek

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  1. K. W. Frischholz
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  2. C. Scholtissek
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Frischholz, K.W., Scholtissek, C. Influence of infection with an influenza A virus (fowl plague) on Ca++-uptake and lipid metabolism of chick embryo cells in culture. Archives of Virology 80, 163–170 (1984). https://doi.org/10.1007/BF01310656

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  • DOI: https://doi.org/10.1007/BF01310656

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