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The influence of the functional state of the central nervous system on the distribution of bromides in some tissues and organs of the albino rat

  • Biochemistry and Biophysics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The effect of various functional states of the central nervous system on the distribution of bromide in rats was studied with the aid of Br82. The various conditions studied were fatigue, period of sleep deprivation from 17 to 72 hr, intoxication with various agents (ether, phenamine, amytal), as well as convulsive shock and supraliminal inhibition caused by the passage of alternating current through the animals' heads. Radioactivity due to Br82 was determined in the blood, thyroid, pituitary, nerves, large hemispheres, mesencephalon, cerebellum, medulla oblongata, adrenals, and muscles.

None of the treatments employed caused any appreciable changes in bromide distribution in brain, but some significant, though slight, changes were observed in the thyroid in some of the experiments.

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Authors and Affiliations

  1. Institute of Biophysics, AN SSSR, Moscow

    I. N. Verkhovskaya & L. M. Tsofina

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  1. I. N. Verkhovskaya
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  2. L. M. Tsofina
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Verkhovskaya, I.N., Tsofina, L.M. The influence of the functional state of the central nervous system on the distribution of bromides in some tissues and organs of the albino rat. Bull Exp Biol Med 51, 46–50 (1961). https://doi.org/10.1007/BF01306876

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  • DOI: https://doi.org/10.1007/BF01306876

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