Some data on the mechanism of antianemin's effect on the hemopoietic processes

Summary

The aim of the work was to determine the role played by the reflex component in the processes of intensified hemopoiesis following administration of antianemin. The study of the blood system reaction to a single administration of the preparation in dogs was followed up by investigation of the effect produced by the same preparation in combination with novocain solution. It appeared that a pronounced, gradually increasing leukocytosis begins to develop three hours after a single dose of antianemin administration. Neutrophilosis is seen with a shift to the left. No quantitative or qualitative changes occur, however, in the white blood after preliminary novocainization of the antianemin injection site. The data obtained demonstrate that the reflex component plays a definite role in the mechanism of antianemin action.