Abstract
The prevalence, predictors, and significance of pneumatosis were determined in 50 patients with Crohn's disease who had abdominal CT scans to rule out abscess. The presence or absence of six CT descriptors and 17 clinical descriptors was documented. CT scans of a control group of 50 subjects without inflammatory bowel disease were also examined. Data was analyzed by two-sample t tests and Fisher's exact test. Pneumatosis was found in six of 50 patients with Crohn's disease and in none of the controls. Corticosteroid treatment was the single clinical variable relating significantly (P=0.025) to pneumatosis, although trends toward absence of resection, short duration of illness, and more severe anemia were also evident in this group. This study suggests that the presence of pneumatosis alone does not dictate a specific course of treatment, but when pneumatosis is present, careful monitoring is required and therapy is based on the overall clinical picture.
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Earnest DL, Schneiderman DJ: Pneumatosis cystoides intestinalis.In Gastrointestinal Disease: Pathophysiology, Diagnosis, Management. M Sleisenger, JS Fordtran (eds). Philadelphia, WB Saunders, 1989, pp 1595–1600
Yale CE: Etiology of pneumatosis cystoides intestinalis. Surg Clin North Am 55:1297–1302, 1975
Rice RP, Thompson WM, Gredgaudas RK: The diagnosis and significance of extraluminal gas in the abdomen. Radiol Clin North Am 20:819–837, 1982
Connor R, Jones B, Fishman EK, Siegelman SS: Pneumatosis intestinalis: Role of computed tomography in diagnosis and management. J Comput Assist Tomogr 8:269–275, 1984
Frik MP, Maile CW, Crass JR, Goldberg ME, Delaney JP: Computed tomography of neutropenic colitis. AJR 143:763–765, 1984
Solomon A, Bar-Ziv J, Stern D, Papo J: Computed tomographic demonstration of intramural colonic air (pneumatosis coli) as a feature of severe ulcerative colitis. Gastrointest Radiol 12:169–171, 1987
Rienhoff WF, Collins NP: Pneumatosis cystoides intestinalis and regional enteritis. Ann Surg 149:593–599 1959
Ghahremani GG, Port RB, Beachley MC: Pneumatosis coli in Crohn's disease. Am J Dig Dis 19:315–323, 1974
Galanduik S, Fazio VW, Petras RE: Pneumatosis cystoides intestinalis in Crohn's disease: Report of two cases. Dis Colon Rectum 28:951–956, 1985
Siskind BN, Burrell MI, Klein ML, Princenthal RA: Toxic dilation in Crohn's disease with CT correlation. J Comput Assist Tomogr 9:193–195, 1985
Suarez V, Chesner IM, Price A, Newman J: Pneumatosis cystoides intestinalis. Histological mucosal changes mimicking inflammatory bowel disease. Arch Pathol Lab Med 113:898–901, 1989
Liechty EJ, Knodell RG, Buckman JF, Strickland RG: Pneumatosis cystoides intestinalis: Mimicry of inflammatory bowel disease. Rocky Mt Med J 76:296–298, 1979
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John, A., Dickey, K., Fenwick, J. et al. Pneumatosis intestinalis in patients with Crohn's disease. Digest Dis Sci 37, 813–817 (1992). https://doi.org/10.1007/BF01300377
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DOI: https://doi.org/10.1007/BF01300377