Skip to main content
SpringerLink
Log in

Granulomatous tonsillitis

A rare extraintestinal manifestation of Crohn's disease

  • Case Report
  • Published:
Digestive Diseases and Sciences Aims and scope Submit manuscript

Summary

Oral lesions, varying in nature and location, appear to be one of the common extraintestinal manifestation of Crohn's disease. In particular, oral involvement preceding intestinal disease may lead to the diagnosis of Crohn's disease. The present case report of a 17-year-old male patient describes a very rare nonintestinal manifestation of Crohn's disease with severe granulomatous involvement of the tonsils. A sore throat caused by hyperplastic tonsils with granulomatous inflammation as an oral manifestation of Crohn's disease was the leading symptom in this case.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Crohn BB, Ginzburg L, Oppenheimer GD: Regional ileitis, a pathologic clinical entity. JAMA 99:1323–1329, 1932

    Google Scholar 

  2. Passo MH, Fitzgerald JF, Brandy KD: Arthritis associated with inflammatory bowel disease in children. Relationship of joint disease to activity and severity of bowel lesion. Dig Dis Sci 31:492–497, 1986

    Google Scholar 

  3. Potsuma R, Moroz SP: Pediatric Crohn's disease. J Pediatr Surg 20:478–482, 1985

    Google Scholar 

  4. Wright R: Crohn's disease: Diagnosis and management. Compr Ther 11:38–44, 1985

    Google Scholar 

  5. Meyers S, Greenspan J, Greenstein AJ: Pancreatitis coincident with Crohn's ileocolitis. Report of a case and review of the literature. Dis Colon Rectum 30:119–122, 1987

    Google Scholar 

  6. Bernstein ML, McDonald JS: Oral lesions in Crohn's disease: Report of two cases and update of the literature. Oral Surg 46:234–245, 1978

    Google Scholar 

  7. Plauth M, Jenss H, Meyle J: Oral manifestations of Crohn's disease—an analysis of 79 cases. J Clin Gastroenterol 13:29–37, 1991

    Google Scholar 

  8. Scully C, Cochran KM, Russell RI, Ferguson MM, Ghouri MA, Lee FD, MacDonald DG, McIntyre PB: Crohn's disease of the mouth: An indicator of intestinal involvement. Gut 23:198–201, 1982

    Google Scholar 

  9. Tyldesley WR: Oral Crohn's disease and related conditions. Br J Oral Surg 17:1–9, 1979

    Google Scholar 

  10. Basu MK, Asquith P: Oral manifestations of inflammatory bowel disease. Clin Gastroenterol 9:307–321, 1980

    Google Scholar 

  11. Clayton R, Feiwel M: Crohn's disease of the mouth. Proc R Soc Med 68:650–651, 1975

    Google Scholar 

  12. Estrin HM, Hughes RW: Oral manifestations in Crohn's disease: A report of a case. Am J Gastroenterol 80:352–354, 1985

    Google Scholar 

  13. Croft CB, Wilkinson AR: Ulceration of the mouth, pharnyx and larynx in Crohn's disease of the intestine. Br J Surg 59:249–252, 1972

    Google Scholar 

  14. Johnson DA, Cattau EL, Hancock JE: Primary Crohn's disease of the oropharnyx. Ear Nose Throat J 64:534–536, 1985

    Google Scholar 

  15. Dudeney TP, Todd IP: Crohn's disease of the mouth. Proc R Soc Med 62:1237, 1969

    Google Scholar 

  16. Dyer NH, Cook PL, Kemp-Harper RA: Oesophageal stricture associated with Crohn's disease. Gut 10:549–554, 1969

    Google Scholar 

  17. Basu MK, Asquith P, Thompson RA, Cooke WT: Oral manifestations of Crohn's disease. Gut 16:249–254, 1975

    Google Scholar 

  18. Boraz AR: Oral manifestations of Crohn's disease: Update of the literature and report of case. J Dent Child 55:72–74, 1988

    Google Scholar 

  19. Coenen C, Börsch G, Müller KM, Fabry H: Oral inflammatory changes as an initial manifestation of Crohn's disease antedating abdominal diagnosis—report of a case. Dis Colon Rectum 31:548–552, 1988

    Google Scholar 

  20. Fedotin MS, Grimmett, Shelburne J: Crohn's disease of the mouth. Am J Dig Dis 19:385–388, 1974

    Google Scholar 

  21. Ferguson MM, MacFadyen EE: Orofacial granulomatosis—a 10 year review. Ann Acad Med 15:370–377, 1986

    Google Scholar 

  22. Frankel DH, Mostofi RS, Lorincz AL: Oral Crohn's disease: Report of two cases in brothers with metallic dysgeusia and a review of the literature. J Am Acad Dermatol 12:260–268, 1985

    Google Scholar 

  23. Ritter RW: Stomatitis granulomatosa as the first symptom of Crohn's disease. Laryngol Rhinol Otol 64:46–48, 1985

    Google Scholar 

  24. Snyder MB, Cawson RA: Oral changes in Crohn's disease. J Oral Surg 34:594–599, 1976

    Google Scholar 

  25. Taylor VE, Smith CJ: Oral manifestations of Crohn's disease without demonstrable gastrointestinal lesions. Oral Surg 39:58–66, 1975

    Google Scholar 

  26. Ward CS, Dunphy EP, Jagoe WS, Sheahan DG: Crohn's disease limited to mouth and anus. J Clin Gastroenterol 7:516–521, 1986

    Google Scholar 

  27. Evans JG: The epidemiology of Crohn's disease. Clin Gastroenterol 1:335–348, 1972

    Google Scholar 

  28. Mekhijan HS, Switz DM, Melnyk CS, Rankin GB, Brooks RK: Clinical features and natural history of Crohn's disease. Gastroenterology 77:898–906, 1979

    Google Scholar 

  29. Sandler RS, Golden AL: Epidemiology of Crohn's disease. J Clin Gastroenterol 8:160–165, 1986

    Google Scholar 

  30. Rogers BH, Clark LM, Kirsner JB: The epidemiologic and demographic characteristics of inflammatory bowel disease: An analysis of a computerized file of 1400 patients. J Chron Dis 24:743, 1971

    Google Scholar 

  31. Farmer RG, Hawk WA, Turnbull RB: Clinical patterns in Crohn's disease: A statistical study of 615 cases. Gastroenterology 68:627–635, 1975

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Internal Medicine and Gastroenterology and Department of Otolaryngology, Community Hospital, Solingen, Germany

    T. Bozkurt MD, M. Langer MD, K. Fendel MD & G. Lux MD

Authors
  1. T. Bozkurt MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. Langer MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. K. Fendel MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. G. Lux MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bozkurt, T., Langer, M., Fendel, K. et al. Granulomatous tonsillitis. Digest Dis Sci 37, 1127–1130 (1992). https://doi.org/10.1007/BF01300298

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01300298

Key Words

Search

Navigation