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Molecular structure and activity of Vicolides isolated fromVicoa indica

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Abstract

Vicolide A to D, sesquiterpenoid lactones, were isolated from “Vicoa indica” and crystal structure of A and D were established by X-ray analysis. The structures were solved by direct methods and refined to an R index of 0.09. Vicolide B and D are reported to have anti-fertility activity while A and C are devoid of this activity. Conformational features of B and C are similar but differ from those of A and C.

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DCB Contribution No. 805.

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Sadasivan, C., Pattabhi, V., Gautham, N. et al. Molecular structure and activity of Vicolides isolated fromVicoa indica . Journal of Crystallographic and Spectroscopic Research 23, 339–344 (1993). https://doi.org/10.1007/BF01263596

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  • DOI: https://doi.org/10.1007/BF01263596

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