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Cell interactions in the generation of chaetae pattern inDrosophila

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Summary

We have already shown that theachaetae-scute complex (AS-C) ofDrosophila is regulated by two genes,hairy andextramacrochaetae. Using mutants in these genes, we have analysed how different levels of expression of AS-C affect the pattern of chaetae. The results indicate that the spatial distribution of chaetae results from cell interactions, probably by a mechanism of lateral inhibition. The results are discussed in view of the different theories of pattern formation.

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References

  • Botas J, Moscoso del Prado J, Garcia-Bellido A (1982) Gene dose titration in the search oftrans-regulatory genes inDrosophila. Embo J 1:307–310

    Google Scholar 

  • Claxton JM (1964) The determination of patterns with especial reference to that of the central primary skin follicles in sheep. J Theor Biol 7:302–317

    Google Scholar 

  • Garcia-Bellido A (1979) Genetic analysis of theachaete-scute system ofDrosophila melanogaster. Genetics 91:491–520

    Google Scholar 

  • Garcia-Bellido A (1981) From the gene to the pattern: chaetae differentiation. In: Lloyd CW, Rees DA (eds) Celular controls in differentiation. Academic Press, London, pp 281–304

    Google Scholar 

  • Garcia-Bellido A (1983) Comparative anatomy of cuticular patterns in the genusDrosophila. In: Goodwin BC, Holder N, Wylie CG (eds) Development and Evolution. Cambridge University Press, Great Britain, pp 227–255

    Google Scholar 

  • Garcia-Bellido A, Merriam JR (1971a) Clonal parameters of targite development in Drosophila. Dev Biol 26:264–276

    PubMed  Google Scholar 

  • Garcia-Bellido A, Merriam JR (1971b) Genetic analysis of cell heredity in imaginal discs ofDrosophila melanogaster. Proc Nalt Acad Sci USA 65:2222–2226

    Google Scholar 

  • Garcia-Bellido A, Santamaria P (1978) Developmental analysis of theachaete-scute system ofDrosophila melanogaster. Genetics 88, 469–486

    Google Scholar 

  • Lawrence PA, Struhl G, Morata G (1979) Bristle patterns and compartment boundaries in the tarsi ofDrosophila. J Embryol Exp Morphol 51:195–208

    PubMed  Google Scholar 

  • Lindsley DL, Grell EH (1968) Genetic variations ofDrosophila melanogaster. Carnegie Inst Wash Publ no 627

  • Meinhardt H, Gierer A (1974), Biological pattern formation involving lateral inhibition. Lect Math Life Sci 7:163–183

    Google Scholar 

  • Moscoso del Prado J (1982) Regulacion genetica del complejoachaete-scute deDrosophila melanogaster. Ph D Thesis Universidad Autonoma de Madrid

  • Moscoso del Prado J, Garcia-Bellido A (1984) Genetic regulation of theachaete-scute complex ofDrosophila melanogaster. 193:242–245

  • Richelle J, Ghysen A (1979) Determination of sensory bristles and pattern formation inDrosophila. I. A model. Dev Biol 70:418–438

    PubMed  Google Scholar 

  • Stern C (1940) The prospective significance of imaginal discs inDrosophila. J Morphol 67:107–122

    Google Scholar 

  • Stern C (1954) Two or three bristles. Am Sci 42:213–247

    Google Scholar 

  • Sturtevant AH (1929) The claret mutant type ofDrosophila simulans: a study of chromosome elimination and cell lineage. Zwiss Zool 135:323–356

    Google Scholar 

  • Sturtevant AH (1970) Studies on the bristle pattern ofDrosophila. Dev Biol 21:48–61

    PubMed  Google Scholar 

  • Tokunaga C (1962) Cell lineage and differentiation on the male foreleg ofDrosophila melanogaster. Dev Biol 4:489–516

    PubMed  Google Scholar 

  • Wigglesworth VB (1940) Local and general factors in the development of pattern inRhodnius prolixus. J Exp Biol 17:180–200

    Google Scholar 

  • Wolpert L (1969) Positional information and the spatial pattern of cellular differentiation. J Theor Biol 25:1–47

    PubMed  Google Scholar 

Download references

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Moscoso del Prado, J., Garcia-Bellido, A. Cell interactions in the generation of chaetae pattern inDrosophila . Wilhelm Roux' Archiv 193, 246–251 (1984). https://doi.org/10.1007/BF01260346

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  • DOI: https://doi.org/10.1007/BF01260346

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