Summary
Vasoactive intestinal polypeptide (VIP) levels and distribution were studied in the penis of young-adult (3-month-old) and old (30-month-old) Wistar rats by radioimmunoassay and immunofluorescence. No significant changes in tissue VIP concentrations or distribution occurred in the penis of old rats compared to young-adult rats. The present data indicate that the age-related impairment of male sexual function is not dependent on modifications of the VIP-ergic innervation of penile tissue.
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Amenta, F., Cavallotti, C., De Rossi, M. et al. Vasoactive intestinal polypeptide levels and distribution in the penis of old rats. J. Neural Transmission 70, 137–143 (1987). https://doi.org/10.1007/BF01252515
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DOI: https://doi.org/10.1007/BF01252515