Conclusion
Mortality rate of white Swiss inbred male mice, weighing 20 to 25 g, exposed to a whole body X-irradiation of 800 r was found to be 70–80 per cent.
The mortality rate was markedly reduced by the serial subcutaneous injection of purified vaccine lymph (P. V. L.) administered one hour after irradiation: survival rate of irradiated mice treated with a total 0.4 cc of live P. V. L. was about 70 per cent, and that of treated with a total 4.0 cc heat-killed P. V. L. (56° X 15′) was more than 80 per cent. The mortality of adult Swiss mice, exposed to 800 r was reduced following a single intraperitoneal injection of spleen homogenate administered one hour after the irradiation. The mice treated with the homogenate equivalent to 2 spleens of young mice survived 53 per cent against 28 per cent in untreated control.
In chlorophyll preparation (Greenpole) entirely no effects were recognized.
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Yaoi, H., Kimura, Y. On therapeutical effects of purified vaccine lymph (P. V. L.) against X-ray injury in mice. Archiv f Virusforschung 6, 118–123 (1955). https://doi.org/10.1007/BF01247061
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DOI: https://doi.org/10.1007/BF01247061