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Rapid serological typing of herpes simplex virus and titration of herpes simplex antibody by the use of mixed hemadsorption — a mixed antiglobulin reaction applied to virus infected tissue cultures

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Summary

The mixed hemadsorption technique, which is essentially a mixed antiglobulin reaction, was used for a direct serological typing of freshly isolated strains of herpes simplex virus in partly degenerated tissue culture tubes. By this method isolation and typing can generally be carried out within 2 or 3 days. The same method was utilized also for the titration of antibody in human sera. Very high specific titers were obtained for post-infectious sera. The height of these titers was only moderately correlated to those obtained by complement fixation and neutralization tests.

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  1. National Bacteriological Laboratory, Stockholm, Sweden

    J. Åke Espmark

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  1. J. Åke Espmark
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Åke Espmark, J. Rapid serological typing of herpes simplex virus and titration of herpes simplex antibody by the use of mixed hemadsorption — a mixed antiglobulin reaction applied to virus infected tissue cultures. Archiv f Virusforschung 17, 89–97 (1965). https://doi.org/10.1007/BF01242603

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  • DOI: https://doi.org/10.1007/BF01242603

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