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Immunofluorescent assay of herpesvirus type 1 and type 2 antibodies in rabbit and human sera

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Summary

The immunofluorescent antibody technique was used to assay type-specific herpes simplex virus antibodies. Antibody responses were studied in three groups of patients: children with primary herpetic infections, neonates with generalized type 2 infection and adults with genital herpes infections. The results were compared with antibody responses seen in rabbits after experimental type 1 and 2 infections. In both rabbits and children with primary herpetic infections there was considerable cross-reaction, while in patients with genital herpes infections and in neonates there was very little cross-reaction.

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  1. Pauli Leinikki

    Present address: Department of Virology, University of Helsinki, Finland

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    1. Pauli Leinikki
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    Leinikki, P. Immunofluorescent assay of herpesvirus type 1 and type 2 antibodies in rabbit and human sera. Archiv f Virusforschung 35, 349–355 (1971). https://doi.org/10.1007/BF01241915

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    • DOI: https://doi.org/10.1007/BF01241915

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