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Attenuation of the hog cholera virus by continuous cell-virus propagation

III. Growth interference of newcastle disease virus by attenuated hog cholera virus and its application to virus titration and the neutralization test

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Summary

A titration method for hog cholera viruses (HCV) of low virulence (strain LOM) has been described. The method, designated the INC-method, is based upon interference between the preinoculated strain LOM and the postinoculated Newcastle disease virus in swine testicle cell cultures.

The INC-method has been shown to be an accurate method for the titration of HCV and neutralizing antibodies and proved to be as sensitive as the swine inoculation test.

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Author notes

  1. U. Sato

    Present address: National Veterinary Assay Laboratory, Tokyo, Japan

Authors and Affiliations

  1. National Veterinary Assay Laboratory, Tokyo, Japan

    T. Hanaki & K. Nobuto

Authors
  1. U. Sato
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  2. T. Hanaki
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  3. K. Nobuto
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Sato, U., Hanaki, T. & Nobuto, K. Attenuation of the hog cholera virus by continuous cell-virus propagation. Archiv f Virusforschung 26, 1–10 (1969). https://doi.org/10.1007/BF01241171

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  • DOI: https://doi.org/10.1007/BF01241171

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