Summary
The preliminary results of an open comparative study of the oral antidiabetic glipizide and tolbutamide have shown that in all patients, except for 1 [2] of 16 glipizide cases and ¦2 [1] of 12 tolbutamide cases, an adequate control of the diabetes could be achieved. There were no side effects besides clinical signs of hypoglycaemia in 4 patients on Glipizide.
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Ambrogi, V., Bloch, K., Daturi, S., Griggi, P., Logemann, W., Parenti, M.A., Rabini, T., Tommasini, R.: New oral antidiabetic drugs part I. Drug. Res.21, 200–204 (1971)
Ambrogi, V., Bloch, K., Cozzi, P., Daturi, S., Logemann, W., Parenti, M.A., Tommasini, R.: New oral antidiabetic drugs part II. Drug. Res.21, 204–208 (1971)
Ambrogi, V., Bloch, K., Daturi, S., Griggi, P., Logemann, W., Mandelli, V., Parenti, M.A., Rabini, T., Usardi, M.M., Tommasini, R.: Pharmacological study on a new oral antidiabetic: N-{4-[β-(5-Methyl-pyrazine 2-earboxamido)-ethyl]-benzene-sulphonyl-N′-cyclohexyl-urea or K 4024. Drug Res.21, 208–215 (1971)
Marigo, S., del Nevo, G., Bini, P.P., Sacchetti, G.: Pharmacological methods for evaluating a new hypoglycaemic agent in humane: a Multistep Design. Drug Res.21, 215–220 (1971)
Pedrazzi, F., Pisani Ceretti, A., Losi, S., Bommartini, F., Artini, D., Emanueli, A.: Evaluation in hospitalized subjects of a new hypoglycaemic sulphonylurea, glydiazinamide. Drug Res.21, 220–225 (1971)
Ambrogi, V., Bloch, K., Daturi, S., Logemann, W., Parenti, M.A., Tommasini, R.: New oral antidiabetic drugs part III. Drug Res.22, 542–544 (1972)
Lentini, S., Bossini, A., Colombo Pirola, L.: A controlled clinical trial of a new oral hypoglycaemic agent, glipizide (K 4024). Drug Res.22, 1169–1173 (1972)
D'Onofrio, F., Pempinello, R., Romis, L.: Clinical and metabolic observations with a new synthetic oral antidiabetic agent, glipizide. Drug Res.22, 1879–1881 (1972)
Emanueli, A., Molari, E., Colombo Pirola, L., Caputo, G.: Glipizide, a new sulphonylurea in the treatment of diabetes mellitus. Drug Res.22, 1881–1885 (1972)
Fedele, D., Tiengo, A., Riva, F., Muggeo, M., Emanueli, A., Crepaldi, G.: Modifications of glycaemia and insulinaemia in diabetes treated with glipizide (K 4024), a new sulphonylurea. Drug Res.22, 1885–1888 (1972)
Vailati, G., Pagani, G., Montini, M., Caputo, G., Sacchetti, G.: Effect of glipizide on a double-meal test in diabetic patients. Drug Res.22, 1888–1889 (1972)
Schliack, V., Mohnicke, H., Rost, H., Honigmann, G., Jahnke, K., Schilling, W., Gutsche, H., Blumenbach, H., Walker, J.B., Kerridge, D., Keen, H., Jarrett, R.J., Eschwege, E., Hoet, J.J., Syllaba, J., Teuscher, A., Glasunov, I., Jaksic, Z., Skrabalo, Z., Andreev, D.: Report of the European Epidemiology Study Group Diabetologia6, 646 (1970)
Teuscher, A., Richterich, R.: Neue schweizerische Richtlinien zur Diagnose des Diabetes mellitus. Schweiz. med. Wschr.101, 345–352, 390–398 (1971)
Frehner, H.U.: Diabetes-Fibel, p. 129. Stuttgart: Georg Thieme 1972
Robbers, H.: Praktische Diabetologie, p. 123. München: Dr. Edmund Banaschewski 1969
Schöffling, K.: Überwachung und Einstellung des Diabetikers. M'Kurse ärztl. Fortb.8, 319–327 (1970)
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Fuchs, K. Glipizide versus tolbutamide in maturity-onset diabetes, an open comparative study. Diabetologia 9 (Suppl 1), 351–355 (1973). https://doi.org/10.1007/BF01218446
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DOI: https://doi.org/10.1007/BF01218446