Abstract
The coulometric titration technique is applied for evaluation of protonation constants of substances available in micromolar amounts. The validity of the procedure was checked by studying several well-known systems. Unknown constants were evaluated for naturally isolated alkaloids. The advantages of the microcoulometric technique are discussed.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
A. Albert, E. P. Serjeant,The Determination of Ionization Constants, Chapman and Hall, London, 1971.
P. Zikolov, O. Budevsky,Talanta 1973,20, 487.
H. Irving, C. F. Bell,J. Chem. Soc. 1952, 1217.
S. Głąb, A. Hulanicki,Talanta 1981,28, 183.
S. Głąb, S. Skrzydlewska, A. Hulanicki,Talanta 1987,34, 411.
O. Achmatowicz, J. T. Wróbel,Tetrahedron Lett. 1964, 129.
O. Achmatowicz, H. Banaszek, G. Spiteller, J. T. Wróbel,Tetrahedron Lett. 1964, 927.
R. T. La Londe, Ch. Wong, W. P. Cullen,Tetrahedron Lett. 1970, 4477.
G. Gran,Analyst 1952,77, 661.
R. S. Kolat, J. E. Powell,Inorg. Chem. 1962,1, 293.
M. Yasuda, K. Yamasuki, M. Ohtaki,Bull. Chem. Soc. Japan 1960,33, 1067.
E. Campi,Ann. Chim. (Italy) 1963,53, 96.
C. P. Timberlake,J. Chem. Soc. 1964, 1229.
K. Kundu, M. M. Das,J. Chem. Eng. Data 1964,82, 9.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Głąb, S., Nowicka, U. Microcoulometric determination of protonation constants of nuphar alkaloids. Mikrochim Acta 92, 229–236 (1987). https://doi.org/10.1007/BF01201844
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF01201844