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Oxytetracycline production byStreptomyces rimosus in solid state fermentation of sweet potato residue

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Abstract

Sweet potato residue, a starchy agricultural waste, was used as a substrate to produce oxytetracycline byStreptomyces rimosus TM-55 in a solid-state fermentation. Oxytetracycline was detected on the third day, reached its maximum value on the sixth day and remained constant to the twentieth day. Optimal conditions for oxytetracycline production were an initial pH of 5.5 to 6.5, supplemented with 20% (w/v) defatted roasted peanut meal, as the sole nitrogen source, 1.0% (w/v) CaCO3 and 2.0% (w/v) MgSO4·7H2O, being incubated at 26 to 35°C for 6 to 7 days. Oxytetracycline reached 12.1 mg/g substrate.

Résumé

On a utilisé des résidus de patates douces, on résidu agricole amylacé, comme substral pour la production d'oxytétracycline parStreptomyces rimosus TM-55 par fermentation en milieu solide. On a détecté foxytétracycline le 3ème jour. Celui-ci a arteint sa concentration maximum le 6ème jour et celle-ci est restée constante jusqu'au 20eme jour. Les conditions optimales pour la production d'oxytétracycline sont les staivanies: un pH initial compris entre 5.5 et 6.5, l'ajout de 20% (p/v) de farine d'arachide dégraissée, comme seule source d'azote, 1.0% (p/v) de CaCO3 et 2.0% (p/v) de MgSO4.7H2O, une température d'incubation de 26 à 35°C pendant 6 à 7 jours. On a aneint 12.1 mg d'oxytetracycline par g de substrat.

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Yang, S.S., Yuan, S.S. Oxytetracycline production byStreptomyces rimosus in solid state fermentation of sweet potato residue. World J Microbiol Biotechnol 6, 236–244 (1990). https://doi.org/10.1007/BF01201291

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