Skip to main content
Log in

Role of the lateral and medial hypothalamus in the reproduction of alimentary and defensive instrumental reactions

  • Published:
Neuroscience and Behavioral Physiology Aims and scope Submit manuscript

Abstract

It was established in experiments on two dogs that a test electrical stimulation of the lateral hypothalamus reproduces an instrumental movement in the case of a developed alimentary instrumental CR to a tone and does not reproduce it in the case of a developed acid defensive instrumental CR. In the case of an electrical stimulation of the medial hypothalamus, the instrumental movement is essentially not reproduced, either in the alimentary or the defensive situations. The appearance of the instrumental movement with electro-stimulation of the LH in the alimentary situation is associated with activation of the backward conditioned connection from the motivational “alimentary” center of the LH to the representation of this movement in the motor cortex.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literature cited

  1. É. A. Asratyan, “The physiology of the reinforcement of the conditioned reflex,”Zhurn. Vyssh. Nervn. Deyat.,21, No. 1, 3–13 (1971).

    Google Scholar 

  2. É. A. Asratyan,Essays on Higher Nervous Activity [in Russian], Izd-vo AN Arm. SSR, Erevan (1977).

    Google Scholar 

  3. J. Gray, “The neuropsychology of the emotions and the structure of the personality,”Zhurn. Vyssh. Nervn. Deyat.,37, No. 6, 1011–1024 (1987).

    Google Scholar 

  4. G. A. Grigor'yan, “The interaction of signal, motivational, and executive components of the conditioned reflex,”Zhurn. Vyssh. Nervn. Deyat.,40, No. 4 (1990).

    Google Scholar 

  5. E. K. Davydova,Movement as Signal [in Russian], Nauka, Moscow (1986).

    Google Scholar 

  6. E. K. Davydova and G. A. Grigor'yan, “The role of the lateral and meidal hypothalamus in the reproduction of a motoric reaction which is the signal during the development of classical conditioned reflexes,”Zhurn. Vyssh. Nervn. Deyat.,41, No. 1, 41–50 (1990).

    Google Scholar 

  7. J. Konorsky,Integrative Brain Activity [Russsian translation], Mir, Moscow (1970).

    Google Scholar 

  8. T. N. Oniani,The Integrative Function of the Limbic System [in Russian], Metsniereba, Tbilisi (1980).

    Google Scholar 

  9. P. V. Simonov,The Emotional Brain [in Russian], Nauka, Moscow (1981).

    Google Scholar 

  10. P. V. Simonov, “The interaction of forward and backward conditioned connections as the neurophysiological basis of motivation and behavior,”Zhurn. Vyssh. Nervn. Deyat.,33, No. 2, 241–247 (1983).

    Google Scholar 

  11. V. M. Storozhuk,The Neuronal Mechanisms of Learning [in Russian], Naukova Dumka, Kiev (1986).

    Google Scholar 

  12. K. V. Sudakov,The Systemic Mechanisms of Motivation [in Russian], Meditsina, Moscow (1979).

    Google Scholar 

  13. L. I. Chilingaryan and G. A. Grigor'yan, “The role of the signal and motivational components of the conditioned reflex in the initiation of instrumental reactions in dogs,”Zhurn. Vyssh. Nervn. Deyat.,40, No. 5, 851–861 (1989).

    Google Scholar 

  14. B. K., Anand and J. R. Brobeck, “Localization of feeding center in the hypothalamus of the rat,”Proc. Soc. Exp. Biol. Med.,77, 323–324 (1951).

    Google Scholar 

  15. E. E. Coons, M. Lewak, and N. E. Miller, “Lateral hypothalamus learning of food seeking response motivated by electrical stimulation,”Science,150, No. 370 (1965).

    Google Scholar 

  16. E. Grastyax, K. Lissak, and F. Kekesi, “Facilitation and inhibition of conditioned alimentary and defensive reflexes by stimulation of the hypothalamus and reticular formation,”Acta Physiol. Acad. Sci. Hung.,19, No. 1–3, 133–146 (1956).

    Google Scholar 

  17. B. G. Hoebel, “Feeding: neural control of intake,”Ann. Rev. of Physiology,33, 533–568 (1971).

    Google Scholar 

  18. F. B. Krasne, “General disruption resulting from electrical stimulation of ventromedial hypothalamus,”Science,138, 822–823 (1962).

    Google Scholar 

  19. R. K. S. Lim, Ch.-N. Liu, and R. L. Moffit,A Stereotaxic Atlas of the Dog's Brain, Charles C. Thomas Publ., Springfield (1960).

    Google Scholar 

  20. N. E. Miller, “Implication for theories of reinforcement,” in:Electrical Stimulation of the Brain, D. E. Sheer (ed.), Univ. Texas Press (1961), pp. 575–581.

  21. H. Nakao, “Emotional behavior produced by hypothalamic stimulation,”Amer. J. Physio!.,194, No. 2, 411–418 (1958).

    Google Scholar 

  22. B. P. H. Poschel, “Comparison of reinforcing effects yielded by lateral versus medial hypothalamic stimulation,”J. Comp. and Physiol. Psychol.,61, No. 3, 346–352 (1966).

    Google Scholar 

  23. K. Rasmussen and B. L. Jacobs, “Single unit activity of locus coeruleus neurons in the freely moving cat. II. Conditioning and pharmacological studies,”Brain Res.,371, No. 2, 335–344 (1986).

    Google Scholar 

  24. W. Wyrwicka, C. Dobrzecka, and R. Tarnecki, “On the instrumental conditioned reaction evoked by electricl stimulation of the hypothalamus,”Science,130, No. 3771, 336–338 (1959).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Translated from Zhurnal Vysshei Nervnoi Deyatel'nosti imeni I. P. Pavlova, Vol. 41, No. 2, pp. 281–290, March–April, 1991.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Davydova, E.K., Grigor'yan, G.A. Role of the lateral and medial hypothalamus in the reproduction of alimentary and defensive instrumental reactions. Neurosci Behav Physiol 22, 104–112 (1992). https://doi.org/10.1007/BF01192381

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01192381

Keywords

Navigation