Abstract
It was established in experiments on two dogs that a test electrical stimulation of the lateral hypothalamus reproduces an instrumental movement in the case of a developed alimentary instrumental CR to a tone and does not reproduce it in the case of a developed acid defensive instrumental CR. In the case of an electrical stimulation of the medial hypothalamus, the instrumental movement is essentially not reproduced, either in the alimentary or the defensive situations. The appearance of the instrumental movement with electro-stimulation of the LH in the alimentary situation is associated with activation of the backward conditioned connection from the motivational “alimentary” center of the LH to the representation of this movement in the motor cortex.
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Literature cited
É. A. Asratyan, “The physiology of the reinforcement of the conditioned reflex,”Zhurn. Vyssh. Nervn. Deyat.,21, No. 1, 3–13 (1971).
É. A. Asratyan,Essays on Higher Nervous Activity [in Russian], Izd-vo AN Arm. SSR, Erevan (1977).
J. Gray, “The neuropsychology of the emotions and the structure of the personality,”Zhurn. Vyssh. Nervn. Deyat.,37, No. 6, 1011–1024 (1987).
G. A. Grigor'yan, “The interaction of signal, motivational, and executive components of the conditioned reflex,”Zhurn. Vyssh. Nervn. Deyat.,40, No. 4 (1990).
E. K. Davydova,Movement as Signal [in Russian], Nauka, Moscow (1986).
E. K. Davydova and G. A. Grigor'yan, “The role of the lateral and meidal hypothalamus in the reproduction of a motoric reaction which is the signal during the development of classical conditioned reflexes,”Zhurn. Vyssh. Nervn. Deyat.,41, No. 1, 41–50 (1990).
J. Konorsky,Integrative Brain Activity [Russsian translation], Mir, Moscow (1970).
T. N. Oniani,The Integrative Function of the Limbic System [in Russian], Metsniereba, Tbilisi (1980).
P. V. Simonov,The Emotional Brain [in Russian], Nauka, Moscow (1981).
P. V. Simonov, “The interaction of forward and backward conditioned connections as the neurophysiological basis of motivation and behavior,”Zhurn. Vyssh. Nervn. Deyat.,33, No. 2, 241–247 (1983).
V. M. Storozhuk,The Neuronal Mechanisms of Learning [in Russian], Naukova Dumka, Kiev (1986).
K. V. Sudakov,The Systemic Mechanisms of Motivation [in Russian], Meditsina, Moscow (1979).
L. I. Chilingaryan and G. A. Grigor'yan, “The role of the signal and motivational components of the conditioned reflex in the initiation of instrumental reactions in dogs,”Zhurn. Vyssh. Nervn. Deyat.,40, No. 5, 851–861 (1989).
B. K., Anand and J. R. Brobeck, “Localization of feeding center in the hypothalamus of the rat,”Proc. Soc. Exp. Biol. Med.,77, 323–324 (1951).
E. E. Coons, M. Lewak, and N. E. Miller, “Lateral hypothalamus learning of food seeking response motivated by electrical stimulation,”Science,150, No. 370 (1965).
E. Grastyax, K. Lissak, and F. Kekesi, “Facilitation and inhibition of conditioned alimentary and defensive reflexes by stimulation of the hypothalamus and reticular formation,”Acta Physiol. Acad. Sci. Hung.,19, No. 1–3, 133–146 (1956).
B. G. Hoebel, “Feeding: neural control of intake,”Ann. Rev. of Physiology,33, 533–568 (1971).
F. B. Krasne, “General disruption resulting from electrical stimulation of ventromedial hypothalamus,”Science,138, 822–823 (1962).
R. K. S. Lim, Ch.-N. Liu, and R. L. Moffit,A Stereotaxic Atlas of the Dog's Brain, Charles C. Thomas Publ., Springfield (1960).
N. E. Miller, “Implication for theories of reinforcement,” in:Electrical Stimulation of the Brain, D. E. Sheer (ed.), Univ. Texas Press (1961), pp. 575–581.
H. Nakao, “Emotional behavior produced by hypothalamic stimulation,”Amer. J. Physio!.,194, No. 2, 411–418 (1958).
B. P. H. Poschel, “Comparison of reinforcing effects yielded by lateral versus medial hypothalamic stimulation,”J. Comp. and Physiol. Psychol.,61, No. 3, 346–352 (1966).
K. Rasmussen and B. L. Jacobs, “Single unit activity of locus coeruleus neurons in the freely moving cat. II. Conditioning and pharmacological studies,”Brain Res.,371, No. 2, 335–344 (1986).
W. Wyrwicka, C. Dobrzecka, and R. Tarnecki, “On the instrumental conditioned reaction evoked by electricl stimulation of the hypothalamus,”Science,130, No. 3771, 336–338 (1959).
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Translated from Zhurnal Vysshei Nervnoi Deyatel'nosti imeni I. P. Pavlova, Vol. 41, No. 2, pp. 281–290, March–April, 1991.
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Davydova, E.K., Grigor'yan, G.A. Role of the lateral and medial hypothalamus in the reproduction of alimentary and defensive instrumental reactions. Neurosci Behav Physiol 22, 104–112 (1992). https://doi.org/10.1007/BF01192381
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DOI: https://doi.org/10.1007/BF01192381