Abstract
Rat recipients were trained to cling to a rotating bar, after which the section of the motor cortex in which the right posterior extremity is represented was removed. On the second day after the operation a lyophilizate of CSF taken from the donors on day 7 following an analogous operation was injected suboccipitally into the recipients. The degree of restoration of the motor function in recipients was assessed from the time of clinging to a rotating bar and the number of slips by the right posterior paw. We determined the optimum dose of the lyophilizate of the liquor from the operated donors whose administration to the recipients with an analogous trauma accelerates restoration of the motor function.
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Translated from Fiziologicheskii Zhurnal SSSR imeni I. M. Sechenova, Vol. 73, No. 12, pp. 1608–1614, December, 1987.
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Loseva, I.V., Silakov, V.L. Effect of csf from animals with damage to the motor cortex on compensation of motor disorders. Neurosci Behav Physiol 19, 139–145 (1989). https://doi.org/10.1007/BF01190459
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DOI: https://doi.org/10.1007/BF01190459