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Cholinergic regulation of neuronal activity in the somatosensory cortex in early postnatal ontogenesis in the cat

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Conclusions

  1. 1.

    In 2-week-old kittens, leas than one fourth of the neurons of the somatosensory cortex react to stimulation of the ascending cholinergic pathways.

  2. 2.

    Cholinergic stimulation in 11–14-day-old kittens induces an inhibition of the background and evoked activation of neurons of the cortex. The duration of inhibition is up to 500 msec.

  3. 3.

    In 2-week-old kittens the cholinergic mechanism of synaptic transmission is weakly expressed and differs significantly from the definitive mechanisms in functional criteria.

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Authors and Affiliations

  1. Institute of Higher Nervous Activity and Neurophysiology, Academy of Sciences of the USSR, Moscow

    V. V. Raevskii & K. P. Budko

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  1. V. V. Raevskii
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  2. K. P. Budko
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Translated from Zhurnal Vysshei Nervnoi Deyatel'nosti imeni I. P. Pavlova, Vol. 36, No. 5, pp. 919–924, September–October, 1986.

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Raevskii, V.V., Budko, K.P. Cholinergic regulation of neuronal activity in the somatosensory cortex in early postnatal ontogenesis in the cat. Neurosci Behav Physiol 17, 421–426 (1987). https://doi.org/10.1007/BF01188732

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  • DOI: https://doi.org/10.1007/BF01188732

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