Conclusions
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1.
The microelectrophoretic application of GABA during the presentation of the pairings rendered difficult the formation of conditioned inhibitory reactions in the neurons of the sensorimotor cortex.
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2.
In neurons whose impulse activity is blocked during the process of the association of stimuli of various modalities, by the application of GABA, or which are initially inactive (the “silent” neurons), the development of conditioned cellular reactions primarily of the activating type is possible.
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3.
It is proposed that conditioned inhibitory reactions arise as the result of plastic reconstructions occurring at the cortical level, in contradistinction to the activating conditioned responses, which are basically determined by shifts at subcortical levels.
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Translated from Zhurnal Vysshei Nervnoi Deyatel'nosti imeni I. P. Pavlova, Vol. 34, No. 6, pp. 1122–1127, November—December, 1984.
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Aleksandrov, A.A., Sabanov, V.S. & Samoilova, L.A. Influence of microiontophorertic application of gaba on the formation of the cellular analog of the conditioned reflex. Neurosci Behav Physiol 17, 106–111 (1987). https://doi.org/10.1007/BF01184899
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DOI: https://doi.org/10.1007/BF01184899