Abstract
4-Hydroxyhexahydropyrimidine-2-thiones were obtained by reaction of N-(azidomethyl)- or N-(p-tlylsulfonylmethyl)thioureas with anions of 1,3-dicarbonyl compounds. The corresponding 1,2,3,6-tetrahydropyrimidine-2-thiones were synthesized by dehydration of the pyrimidines obtained.
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Shutalev, A.D., Kuksa, V.A. Novel method for synthesis of 4-hydroxyhexahydropyrimidine-2-thiones. Chem Heterocycl Compd 31, 86–91 (1995). https://doi.org/10.1007/BF01171299
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DOI: https://doi.org/10.1007/BF01171299