Abstract
Reactions of 1, 3-isothiocyanato ketones with mineral acids formed 3, 4-dihydro-2H, 1, 3-thiazin-2-ones or their mixtures with 6-alkylidenetetrahydro-1, 3-thiazin-2-ones. Subsequent acid hydrolysis of the thiazines obtained formed salts of 1,3-amino ketones. The direction and extent of the transformation depend on the nature of the acid, reaction temperature, and structure of the 1,3-isothiocyanato ketones.
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Additional information
Omsk State University, Omsk 644077. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 850–854, June, 1996. Original article submitted October 18, 1995.
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Fisyuk, A.S., Peretokin, A.V., Ryzhova, E.A. et al. Reactions of 1,3-isothiocyanato ketones with mineral acids. Synthesis of 3,4-dihydro-2H,1,3-thiazin-2-ones. Chem Heterocycl Compd 32, 732–736 (1996). https://doi.org/10.1007/BF01164876
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DOI: https://doi.org/10.1007/BF01164876