Skip to main content
SpringerLink
Log in

A possible adenine nucleotide storage form in normal and ischaemic rat heart

  • Published:
Bioscience Reports

Abstract

Perfusion of Langendorff rat hearts with [14C]adenosine yields an acid-insoluble, radioactive product whose concentration falls during ischaemia. The properties of the substance show that it is a polyribonucleotide. It is suggested that it may be mitochondrial poly A acting as a storage form of adenine nucleotides.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Bates DJ, Perrett D & Mowbray J (1978) Biochem. J.176, 485–493.

    PubMed  Google Scholar 

  • Berne RM & Rubio R (1974) Circ. Res.34–35 (Suppl. 2), 109–120.

    Google Scholar 

  • Friedman WF, Buccino FA, Sonnenblick EH & Braunwald E (1967) Circ. Res.21, 573–582.

    PubMed  Google Scholar 

  • Gajda AT, Behrens G & Fitt PS (1970) Biochem. J.120, 753–761.

    PubMed  Google Scholar 

  • Hohorst HJ, Rein M & Bartels H (1962) Biochem. Biophys. Res. Commun.7, 142–146.

    PubMed  Google Scholar 

  • Hutchinson WL, Bates DJ, Perrett D & Mowbray J (1981) Biosci. Rep.1, 857–863.

    PubMed  Google Scholar 

  • Jennings RB, Hawkins HK, Lowe JE, Hill ML, Klotman S & Reimer KA (1978) Amer. J. Pathol.92, 187–214.

    Google Scholar 

  • Mowbray J, Bates DJ & Perrett D (1981) FEBS Lett.131, 55–59.

    PubMed  Google Scholar 

  • Randerath K & Randerath E (1967) Meth. Enzymol.12A, 323–347.

    Google Scholar 

  • See YP & Fitt PS (1972) Biochem. J.130, 355–362.

    PubMed  Google Scholar 

  • Swain JL, Sabina RL, McHale PA, Greenfield JC Jr & Holmes EW (1982) Amer. J. Physiol.242, H818-H826.

    PubMed  Google Scholar 

  • Takeo S & Sakanashi M (1983) J. Mol. Cell. Cardiol.15, 577–594.

    PubMed  Google Scholar 

  • Watanabe F, Kamiike W, Nishimura T, Hashimoto T & Tagawa K (1983) J. Biochem.94, 493–499.

    PubMed  Google Scholar 

  • Young HH, Shimizu T, Nishioka K, Nakenishi T & Jarmakani JM (1983) Amer. J. Physiol.245, 998–1006.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biochemistry, University of Ottawa, K1N 9B4, Ottawa, Ontario, Canada

    Peter S. Fitt & Nishi Sharma

  2. Department of Physiology, University of Ottawa, K1N 9B4, Ottawa, Ontario, Canada

    Borivoj Korecky

Authors
  1. Peter S. Fitt
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Borivoj Korecky
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Nishi Sharma
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fitt, P.S., Korecky, B. & Sharma, N. A possible adenine nucleotide storage form in normal and ischaemic rat heart. Biosci Rep 5, 7–12 (1985). https://doi.org/10.1007/BF01117435

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01117435

Keywords

Search

Navigation