Abstract
Rats with a gentic deficiency of phosphorylase kinase have been treated with the 1,4-α-glucosidase inhibitor, Acarbose. Lysosomal glycogen metabolism has been markedly altered and the results support the concept of a feedback control mechanism operating on the uptake mechanism into the lysosomal compartment.
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Geddes, R., Taylor, J.A. Factors affecting the metabolic control of cytosolic and lysosomal glycogen levels in the liver. Biosci Rep 5, 315–320 (1985). https://doi.org/10.1007/BF01116903
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DOI: https://doi.org/10.1007/BF01116903