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The dynamic structures of proteins: Short and long neurotoxins as examples

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Bioscience Reports

Abstract

This review illustrates the way in which nuclear-magnetic-resonance studies of proteins in solution can add dynamic structural information to our knowledge of their crystal structures. The value of the study is illustrated by an analysis of the structure and the dynamics of structure within two series of neurotoxins. The dynamics may well control the binding rates of these and other proteins to receptors.

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Authors and Affiliations

  1. Inorganic Chemistry Laboratory, University of Oxford, South Parks Road, OX1 3QR, Oxford, UK

    Fuyuhiko Inagaki & Robert J. P. Williams

  2. Department of Biophysics and Biochemistry, Faculty of Science, University of Tokyo, 113, Bunkyo-ku, Tokyo, Japan

    Tatsuo Miyazawa

Authors
  1. Fuyuhiko Inagaki
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  2. Tatsuo Miyazawa
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  3. Robert J. P. Williams
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Inagaki, F., Miyazawa, T. & Williams, R.J.P. The dynamic structures of proteins: Short and long neurotoxins as examples. Biosci Rep 1, 743–755 (1981). https://doi.org/10.1007/BF01114796

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  • DOI: https://doi.org/10.1007/BF01114796

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