Abstract
Neuronal responses of an isolated slab of auditory cortex (area AI) to intracortical stimulation at the level IV were studied in curarized cats by extracellular recording 3 weeks after isolation. Dispersion of response latencies in the isolated slab was reduced (compared with that observed soon after isolation); the predominant responses were mono- and disynaptic, and the number of discharges consisting of bursts of spikes increased. However, despite simplification of the structural and functional organization of the chronically isolated slab of auditory cortex, the conditions for complex polysynaptic interaction between neurons of all layers were preserved in it, and in each layer the character of such interaction depended on the distance of the neuron from the focus of origin of the excitation. [In the chronically isolated slab of auditory cortex, just as in the acutely isolated slab, late reponses of over 40 msec were absent.]
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Literature cited
J. Szentagothai, "On synaptology of the cerebral cortex," in: Structure and Functions of the Nervous System [in Russian], Meditsina, Moscow (1962), pp. 6–14.
F. N. Serkov and E. D. Genis, "Structural changes in the synaptic apparatus in a chronically isolated slab of the cat cortex," Fiziol. Zh. (Ukr.),26, No. 4, 524 (1980).
F. N. Serkov, Electrophysiology of Higher Levels of the Auditory System [in Russian], Naukova Dumka, Kiev (1977).
V. D. Taranenko and M. A. Rabtsevich, "Neuronal responses in an isolated slab of the cat auditory cortex to intracortical stimulation," Neirofiziologiya,14, No. 1, 85 (1982).
Zh. P. Shuranova, Investigation of Elementary Working Mechanisms in the Mammalian Cerebral Cortex [in Russian], Nauka, Moscow (1977).
O. Creutzfeldt and G. Struck, "Neurophysiologie und Morphologie der chronisch isolierten Cortexinsel der Katze: Hirnpotentiale und Neurontatigkeit einer isolierten Nervenzellpopulation ohne afferente Fasern," Arch. Psychiat. Z. Neurol.,203, No. 6, 708 (1962).
J.-C. Hirsch, H. J. Iandau, J.-F. Hirsch, and J. Scherrer, "Electrocorticogramme et activites unitaires d'un gyrus cortical isole en preparation chronique," J. Physiol. (Paris),61, No. 5, 387 (1969).
R. Spehlmann, "Acetylcholine and the apileptiform activity of chronically isolated cortex. 2. Microelectrode studies," Arch. Neurol.,24, No. 5, 495 (1971).
J. Rosenthal, H. Waller, and V. E. Amassian, "An analysis of the activation of motor cortical neurons by surface stimulation," J. Neurophysiol.,30, No. 6, 844 (1967).
S. Watanabe and H. Yuasa, "Neuronal activity in the isolated slabs of the cat," Jpn. J. Physiol.,20, No. 6, 672 (1970).
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I. I. Mechnikov Odessa State University. Translated from Neirofiziologiya, Vol. 14, No. 5, pp. 462–469, September–October, 1982.
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Taranenko, V.D., Rabtsevich, M.A. Neuronal responses of an isolated slab of cat auditory cortex to intracortical stimulation. Neurophysiology 14, 336–341 (1982). https://doi.org/10.1007/BF01073213
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DOI: https://doi.org/10.1007/BF01073213