Abstract
A method of continuous external perfusion was used to study the effect of adrenalin and noradrenalin on the excitability of single isolated mechanoreceptors of Pacinian corpuscles. On the addition of adrenalin and noradrenalin in concentrations of 1·10−5–1·10−7 g/ml to the solution the excitability of the receptors was increased by 10–15% and the amplitude of the receptor potential rose on the average by 10–20%. It is postulated that the change in excitability is due to an increase in the receptor membrane potential. The results are discussed in connection with the possible adrenergic innervation of the Pacinian corpuscles.
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I. P. Pavlov Institute of Physiology, Academy of Sciences of the USSR, Leningrad. Translated from Neirofiziologiya, Vol. 6, No. 3, pp. 312–317, May–June, 1974.
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Akoev, G.N., Chelyshev, Y.A. & Él'man, S.I. Effect of catecholamines on excitability of single mechanoreceptors of Pacinian corpuscles. Neurophysiology 6, 248–252 (1974). https://doi.org/10.1007/BF01062424
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DOI: https://doi.org/10.1007/BF01062424