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Distribution of norepinephrine-containing neurons projecting to the parietal association cortex and spinal cord in the cat locus coeruleus

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Abstract

Distribution of neurons forming projections to the parietal association cortex and spinal cord in the cat locus coeruleus (LC) was investigated by means of horseradish peroxidase retrograde transport and catecholamine histofluorescence techniques. Neurons projecting to the parietal cortex were found to be located mainly dorsally within the LC; largest numbers were observed on frontal plane P-1.0. Cells forming projections to the spinal cord were found in the ventral locus coeruleus; highest numbers of these were noted on frontal plane P-3.0. Labeled neurons were also identified in the midbrain reticular formation, pons, and medulla when applying horseradish peroxidase to the parietal cortex and spinal cord. Neurons projecting to the neocortex and spinal cord make up two different populations in the locus coeruleus, indistinguishable on grounds of neuronal morphological characteristics. It was concluded that the cat parietal association cerebral cortex, in common with the spinal cord, receives direct afferent inputs from the locus coeruleus and the reticular formation.

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Authors
  1. A. I. Semenyutin
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  2. V. A. Maiskii
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Additional information

A. A. Bogomolets Institute of Physiology, Academy of Sciences of the Ukrainian SSR, Kiev. Translated from Neirofiziologiya, Vol. 21, No. 1, pp. 112–121, January–February, 1989.

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Semenyutin, A.I., Maiskii, V.A. Distribution of norepinephrine-containing neurons projecting to the parietal association cortex and spinal cord in the cat locus coeruleus. Neurophysiology 21, 96–104 (1989). https://doi.org/10.1007/BF01059110

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  • DOI: https://doi.org/10.1007/BF01059110

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