Abstract
No more than 4% of the miniature endplate potentials (MEPP) recorded in preparations of frog cutaneous pectoral muscle kept in Ringers solution or treated with nonimmune rabbit serum were atypical, having a normal amplitude but abnormally retarded (almost doubled) time course. The percentage of atypical MEPP more than tripled after processing preparations with galactocerebroside (GalC) antiserum. Armine-induced blockade of synaptic acetylcholinesterase increased the rate of "giant" MEPP occurrence (but not of those with normal amplitude plus protracted time course). Mechanisms possibly underlying the increased percentage of atypical MEPP during GalC action on Schwann cells are discussed.
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I. P. Pavlov Institute of Physiology, Academy of Sciences of the USSR, Leningrad. Translated from Neirofiziologiya, Vol. 21, No. 2, pp. 217–223, March–April, 1989.
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Vinogradova, I.M., Dobretsov, M.G., Matyushkin, D.P. et al. Effect of antibodies to glial glycolipid antigens on miniature endplate potentials. Neurophysiology 21, 164–169 (1989). https://doi.org/10.1007/BF01056976
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DOI: https://doi.org/10.1007/BF01056976