Abstract
Spike activity pattern of 34 slow-adapting pulmonary receptors (SAR) was investigated in anesthetized cats during relaxed respiration and forced inhalation of CO2. It was found that approximately one half of the SAR investigated did not differ substantially from relaxed breathing and showed regular intensification in relation to lung stretch. The frequency-volume plot underwent a shift to the right (or else a steeper rise in frequency during inspiration) under these conditions in most of the other receptors. All test SAR showed a reduction in firing rate during exhalation. The pattern of frequency-volume relationship at lung volumes not exceeding respiratory volume was not disrupted. A reduction in firing rate occurred with respiration in all the SAR investigated. The summated spike train from SAR, characterized by averaged frequency of the latter's spike activity, showed a linear dependence on lung volume during both forced and relaxed respiration alike but frequency rose more sharply in the former. Reasons for the changed activity of test SAR during forced breathing are discussed together with possible consequences of these changes for reflex regulation of time phases during the respiratory cycle.
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A. A. Bogomolets Institute of Physiology, Academy of Sciences of the Ukrainian SSR, Kiev. Translated from Neirofiziologiya, Vol. 21, No. 5, pp. 629–636, September–October, 1989.
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Fenik, V.B. Spike activity in pulmonary slow-adapting receptors during forced breathing. Neurophysiology 21, 446–451 (1989). https://doi.org/10.1007/BF01052876
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DOI: https://doi.org/10.1007/BF01052876