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Dehydroepiandrosterone- and glucose-6-phosphate-dehydrogenases in the hair cycle of the rat

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Summary

A histochemical study of dehydroepiandrosterone-dehydrogenase and of glucose-6-P-dehydrogenase during the hair cycle of the rat has been carried out.

Apart from the typical localization of each enzyme, a fair amount of activity of both enzymes was found in fibroblasts and in the adipose tissue during the last part of anagen.

In this phase a strong reaction for glucose-6-P-dehydrogenase was found in the panniculus carnosus.

The possible biochemical significance of these observations is discussed.

Zusammenfassung

Die Aktivität der Dehydroepiandrosteron-Dehydrogenase und der Glucose-6-Phosphat-Dehydrogenase im Verlaute des Haarcyclus bei Ratten wurde histochemisch untersucht. Während des zeitlich letzten Teils des Anagenstadiums zeigte sich unabhängig von der typischen Lokalisation eine schwache Aktivität beider Enzyme in Fibroblasten und im Fettgewebe. Während dieser Zeit war eine starke Reaktion der Glucose-6-Phosphat-Dehydrogenase im Panniculus carnosus zu beobachten. Die mögliche biochemische Bedeutung dieser Ergebnisse wird diskutiert.

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Authors and Affiliations

  1. Research Laboratory of the Dermatologic Clinic of the University of Genoa, Medical School, Genoa, Italy

    F. Crovato, G. Moretti & A. Girard

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  1. F. Crovato
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  2. G. Moretti
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  3. A. Girard
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Crovato, F., Moretti, G. & Girard, A. Dehydroepiandrosterone- and glucose-6-phosphate-dehydrogenases in the hair cycle of the rat. Arch. Derm. Forsch. 240, 55–60 (1971). https://doi.org/10.1007/BF01036167

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  • DOI: https://doi.org/10.1007/BF01036167

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