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Effect of carbon dioxide on the growth of cell suspensions ofCathakanthus roseus

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Summary

Growth parameters of Catharanthus roseus in suspension cultures were examined under various pCO2 conditions. In CO2-enriched environments (up to 2 %) for Erlenmeyer flask cultures, enhanced maximum growth rates and conversion yields were observed. Fermenter cultures with a constant pCO2 of 2 %, gave high conversion yields although no growth-promoting activity was observed. High aeration rates led to decreased rates of growth due to CO2 stripping.

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Maurel, B., Pareilleux, A. Effect of carbon dioxide on the growth of cell suspensions ofCathakanthus roseus . Biotechnol Lett 7, 313–318 (1985). https://doi.org/10.1007/BF01030277

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