Summary
The toxicities of tri-butyl phosphate (TBP) and 2-tert-butyl phenol (OTBP) on the growth ofSaccharomyces cerevisiae were investigated. The toxicity of TBP was reduced by using the inoculum adapted in the medium containing 0.1% (v/v) TBP. OTBP exerted no toxicity in a concentration up to 0.3% (v/v) by adaptation and adding nontoxic solvent 1% (v/v) di-butyl phthalate (DBP). The adaptation resulted in the reduction of hydrophobicity of the cell surface.
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References
Cho, T., and M.L. Shuler (1986).Biotech. Progress, 2(1), 53–60.
Wang, H.Y., L.A., Kominek, and J.L. Jost (1981). On-Line Extraction Fermentation Processes. In:Advances in Biotechnology, M. Moo-Young ed. vol. 1, pp. 601–607, Tronto: Pergamon Press.
Honda, H., M. Taya, and T. Kobayashi (1986).J. Chem. Eng. Japan,19, 268–273.
Matsumura, M., and H. Märkl (1986).Biotech. Bioeng.,28, 534–541.
Pye, E.K., and A.E. Humphrey (1979). Univ. Penn. Interim Report to U.S.D.O.E., June–Aug.
Roddy, J.W. (1981).Ind. Eng. Chem. Process Des. Dev.,20, 104–108.
Rosenberg M., D. Guntnick, and E. Rosenberg (1980).FEMS Microbiology Letters,9, 29–33.
Slodki, M.E. (1980). Structural Aspects of Exocellular Yeast Polysaccharides. In:Fungal Polysaccharides, P. A. Sanford and K. Matsuda, eds. pp. 183–196, Washington, D.C.: American Chemical Society.
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Park, Y.S., Chang, H.N. & Kim, B.H. Adaptation ofSaccharomyces cerevisiae to solvents used in extractive fermentation. Biotechnol Lett 10, 261–266 (1988). https://doi.org/10.1007/BF01024416
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DOI: https://doi.org/10.1007/BF01024416