Summary
The enantioselective potential ofRhodococcus rhodochrous NCIMB 11216 nitrilase has been measured, using a range of chiral nitriles with various C-2 group substitutions. The highest selectivity was achieved during the biotransformation of (+/−) 2-methylhexanitrile where the reaction appears enantiospecific for the (+) enantiomer.
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Gradley, M.L., Knowles, C.J. Asymmetric hydrolysis of chiral nitriles byRhodococcus rhodochrous NCIMB 11216 nitrilase. Biotechnol Lett 16, 41–46 (1994). https://doi.org/10.1007/BF01022621
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DOI: https://doi.org/10.1007/BF01022621