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A novel baker's yeast mediated C-C bond cleavage reaction

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Summary

A novel baker's yeast mediated C−C bond cleavage reaction was observed during the biotransformation of dimethone derivative of thiophene-2-carboxaldehyde (II) to give the product 2-(2′-thienyl methyl)-5,5 dimethyl cyclohexa 1,3-dione (III) in 47% yield.

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Srinivas, M., De, K.B. A novel baker's yeast mediated C-C bond cleavage reaction. Biotechnol Lett 14, 679–682 (1992). https://doi.org/10.1007/BF01021642

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