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Antigenstimulation peripherer Leukozyten von Patienten mit akuten Leukämien

PHA- and PWM-stimulation in acute leukaemia

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Summary

Peripheral blood cells from patients with acute leukaemia were stimulated in RPMI-medium with Phytohaemagglutinin (PHA) and/or Pokeweed-Mitogen (PWM). Samples of the cultures were taken at 3, 5 and 7 day intervals for cytological characterization. From 119 cultures from 65 patients 76 cultures from 47 patients could be analysed. Cultures stimulated with PHA and/or PWM showed in 43,4% a higher stimulation rate in comparison with cultures from normal persons. These findings are discussed in relation to the increased agar-colony growth of leukaemic cells after in vitro PHA-stimulation and transformation of blast cells.

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  1. II. Innere Abteilung, Krankenhaus Neukölln, Rudower Straße 56, D-1000, Berlin 47

    K. -M. Koeppen & I. Boll

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  1. K. -M. Koeppen
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  2. I. Boll
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Koeppen, K.M., Boll, I. Antigenstimulation peripherer Leukozyten von Patienten mit akuten Leukämien. Blut 36, 347–351 (1978). https://doi.org/10.1007/BF01000592

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  • DOI: https://doi.org/10.1007/BF01000592

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