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The intramolecular rearrangement of substituted 4-hydroxyhexahydropyrimidine-2-thiones

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

It has been found that, on being heated with 36% hydrochloric or 85% orthophosphoric acid, substituted 4-hydroxyhexahydropyrimidine-2-thiones (IA) undergo an intramolecular rearrangement connected with the transformation of the cyclic forms IA into the linear tautomers IB and accompanied by dehydration with the formation of substituted 2-alkylamino- or 2-arylamino-4H-1, 3-thiazines.

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Authors and Affiliations

  1. Lomonosov Moscow Institute of Precision Chemical Engineering, USSR

    B. V. Unkovskii & L. A. Ignatova

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  1. B. V. Unkovskii
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  2. L. A. Ignatova
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Unkovskii, B.V., Ignatova, L.A. The intramolecular rearrangement of substituted 4-hydroxyhexahydropyrimidine-2-thiones. Chem Heterocycl Compd 5, 667–669 (1969). https://doi.org/10.1007/BF00957386

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  • DOI: https://doi.org/10.1007/BF00957386

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