Conclusions
The 2-azido derivatives which are formed when 2-chloro-3-(4-acylpiperazino)-1,4-naphthoquinones are reacted with NaN3 in DMF are converted during the reaction to the corresponding 2-amino derivatives and the cyclization products-naphthimidazolediones.
2. It is shown that the precursors of the naphthimidazolediones are 1-(3-amino-1,4-naphthoquinonyl-2)-1,4,5,6-tetrahydropyrazines, which are products from dehydrogenation of the piperazine ring.
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 12, pp. 2822–2826, December, 1988.
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Berezhnaya, V.N., Shishkina, R.P. & Fokin, E.P. Thermal conversions of 2-azido-3-piperazino-substituted 1,4-naphthoquinones. Russ Chem Bull 37, 2545–2549 (1988). https://doi.org/10.1007/BF00952637
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DOI: https://doi.org/10.1007/BF00952637