Abstract
3-(ω-Phthalimidoalkyl)-5-carbethoxymethylenehydantoins were synthesized by the reaction ofω-phthalimidoalkylureas with ethyl oxalacetate and then converted to 3-(ω-aminoalkyl)orotic acids. Condensation of the latter with 6-chloropurine yielded 3-[ω-(6-purinylamino)alkyljorotic acids.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 397–399, March, 1971.
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Berlin, A.Y., Korbukh, I.A. Synthesis ofω-substituted 3-alkylorotic acids. Chem Heterocycl Compd 7, 366–368 (1971). https://doi.org/10.1007/BF00944425
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DOI: https://doi.org/10.1007/BF00944425