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Acquisition of host proteins by the tegument ofSchistosoma mansoni recovered from rats

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Abstract

Four-week-oldSchistosoma mansoni collected from experimentally infected albino rats were shown by a fluorescent antibody technique to possess several serum proteins of host origin, including IgM, IgG, complement and red blood cell components. The capacity of these ratderived worms to acquire and shed host proteins was also demonstrated in vitro with fluoresceinated antibody-labelled worms in the presence of xenogeneic molecules. The implications of these results are discussed in relation to the mechanisms of parasite evasion and “self-cure” phenomenon.

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Author notes

  1. P. K. Das

    Present address: Department of Dermatology, Academic Medical Centre, The Municipal University of Amsterdam, Amsterdam, The Netherlands

Authors and Affiliations

  1. Regional Veterinary Laboratory, P.O. Box 406, 3300, Hamilton, Victoria, Australia

    W. K. Yong

  2. Former International Immunology Training and Research Centre, Plesmanlaan 125, 1066 CS, Amsterdam, The Netherlands

    P. K. Das

Authors
  1. W. K. Yong
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  2. P. K. Das
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Yong, W.K., Das, P.K. Acquisition of host proteins by the tegument ofSchistosoma mansoni recovered from rats. Z. Parasitenkd. 69, 53–60 (1983). https://doi.org/10.1007/BF00934010

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  • DOI: https://doi.org/10.1007/BF00934010

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