Abstract
Antihenic differences among soluble extracts of Y, CL, SF, and Colombian strain epimastigotes ofTrypanosoma cruzi have been demonstrated by crossed immunoelectrophoresis with an intermediate gel containing the heterologous antiserum. Using crossed immunoelectrophoresis with the homologous antiserum, over 30 precipitin lines could be demonstrated for each strain and, even though marked differences were observed in experimental infections, the strains shared a significant number of antigens. In addition, some strain-particular antigens were isolated using affinity chromatography. These antigens could be valuable in the study of biological, immunological, and pathological characteristics of experimental and naturalT. cruzi infections.
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Morgado, M.G., Van Hoegaerden, M. & Galvão-Castro, B. Antigenic analysis ofTrypanosoma cruzi strains by crossed immunoelectrophoresis: demonstration and isolation of antigens particular to some strains. Z. Parasitenkd. 71, 169–178 (1985). https://doi.org/10.1007/BF00926267
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DOI: https://doi.org/10.1007/BF00926267