Conclusions
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1.
A method has been developed for synthesizing previously unknown macrocyclic keto lactones containing a thiophene and fused benzene ring from thiophene.
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2.
Reductive desulfurization of the system containing the thiophene ring gives a 14-membered macrocyclic lactone, viz., 3,4-benzooxacyclotetradecane-2,5-dione (1'-keto-2,4-didesoxy-norzearalane).
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3.
The corresponding lactone and hydroxy lactone with a fused benzene ring are obtained by varying the reductive desulfurization conditions.
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 1, pp. 147–153, January, 1977.
See [1] for communication 19.
See [2 for nomenclauture of macrocyclic compound containing a thiophene ring.
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Alashev, F.D., Bulgakova, V.N., Gol'dfarb, Y.L. et al. Synthesis of macrocyclic compounds. Russ Chem Bull 26, 126–131 (1977). https://doi.org/10.1007/BF00921508
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DOI: https://doi.org/10.1007/BF00921508