Abstract
Water movement from the vitreous to the choroid would tend to maintain retinal apposition, if the retina were less permeable than the retinal pigment epithelium (RPE). We used a rabbit model, to test the relative permeability of retina and RPE to tritiated water. The retina was found less permeable than the RPE. This result suggests the presence of a hydrostatic pressure gradient across the retina which could enhance apposition of retina to the RPE.
Similar content being viewed by others
References
Foulds WS. Basic aspects and practical considerations in retinal detachment surgery. Aust N Z J Ophthalmol 1986; 14: 113–20.
Fatt I, Shantinath K. Flow conductivity of retina and its role in retinal adhesion. Exp Eye Res 1971; 12: 218–26.
Fowlks WL. Meridional flow from the corona ciliaris through the pararetinal zone of the rabbit vitreous. Invest Ophthalmol 1963; 2: 63–71.
Hayreh SS. Posterior drainage of the intraocular fluid from the vitreous. Exp Eye Res 1966; 5: 123–44.
Pederson JE, Cantrill HL. Experimental retinal detachment. V. Fluid movement through the retinal hole. Arch Ophthalmol 1984; 102: 136–9.
Kinsey VE, Grant M, Cogan DG. Water movement and the eye. Arch Ophthalmol 1942; 27: 242–52.
Moseley H, Foulds WS, Allan D et al. Routes of clearance of radioactive water from the rabbit vitreous. Br J Ophthalmol 1984; 68: 145–51.
House CR. Water transport in cells and tissues. Edward Arnold, London, pp 70, 1974.
Foulds WS, Allan D, Moseley H et al. Effect of intravitreal hyaluronidase on the clearance of tritiated water from the vitreous to the choroid. Br J Ophthalmol 1985; 69: 529–32.
Orr G, Goodnight R, Lean JS. Relative permeability of retina and retinal pigment epithelium to the diffusion of tritiated water from vitreous to choroid. Arch Ophthalmol 1986; 104: 1678–80.
Nilsson SEG, Knave B, Persson HE. Changes in ultrastructure and function of the sheep pigment epithelium and retina induced by sodium iodate. II. Early effects. Acta Ophthalmol 1977; 55: 1007–26.
Noell WK. The origin of the electroretinogram. Am J Ophthalmol 1954; 38(Suppl): 78–93.
Karwoski CJ, Frambach DA, Proenza LM. Laminar profile of resistivity in frog retina. J Neurophysiol 1985; 54: 1607–19.
Negi A, Marmor MF. Quantitative estimation of metabolic transport of subretinal fluid. Invest Ophthalmol Vis Sci 1986; 27: 1564–8.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kirchhof, B., Ryan, S.J. Differential permeance of retina and retinal pigment epithelium to water: implications for retinal adhesion. Int Ophthalmol 17, 19–22 (1993). https://doi.org/10.1007/BF00918862
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00918862