Skip to main content
Log in

Study on the aqueous humor flow measured by fluorophotometry after argon laser trabeculoplasty

  • Published:
International Ophthalmology Aims and scope Submit manuscript

Abstract

We have investigated the variations in the aqueous humor flow (F) after argon laser photocoagulation (ALT) in the trabecular meshwork. The research has been done on 60 eyes with primary open angle glaucoma within initial stages. The argon laser trabeculoplasty was made around 360 degrees in anterior trabecular meshwork with 100 burns. The flow (F) has been studied by fluorophotometry using Yablonsky's protocol. Aqueous humor flow has been measured after 24 hours and after 7 days, to determine the immediate effects of laser trabeculoplasty; and also after 6 months for the long term effects. The initial aqueous humor flow was 1.35μl/min. By means of ANOVA we found statistically significant differences on aqueous humor flow after the 7th day (F=1.67μ/min, p<0.01), which remain six months later (F=1.71μl/min, p<0.01). This findings suggest that the effects of argon laser trabeculoplasty, either by mechanical or biological changes in the trabecular meshwork do not appear until the 7th day and remain throughout the follow up study.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Alvarado J, Murphy C, Juster R. Trabecular meshwork cellularity in POAG and non glaucomatous normals. Ophthalmology 1984; 91: 564–70.

    Google Scholar 

  2. Anselmi P, Bron AJ, Maurice DM. Action of drugs on the aqueous flow in man measured by fluorophotometry. Exp Eye Res 1968; 7: 487–92.

    Google Scholar 

  3. Araie M, Sawa M, Nagataki S, Mshima S. Aqueous humor dynamics in man as studied by oral fluorescein. Jpn J Ophthalmol 1980; 24: 346–50.

    Google Scholar 

  4. Araie M, Takase M. Effects of S 596 carteolol, a new beta-adrenergic blockers, and flubiprofen on the human eye: a fluorophotometric study. Graeffe's Arch Clin Exp Ophthalmol 1985; 222: 259–65.

    Google Scholar 

  5. Araie M, Yamamoto T, Shirato S. Effects of laser trabeculoplasty on the human aqueous humor dynamics: a fluorophotometric study. Ann Ophthalmol 1984; 16: 541–45.

    Google Scholar 

  6. Brubaker RF, McLaren JW. Uses of fluorophotometry in glaucoma research. Ophthalmology 1985; 92: 884–90.

    Google Scholar 

  7. Brubaker RF, Liesegang TJ. Effects of trabecular photocoagulation on the aqueous humor dynamics of the human eye. Am J Ophthalmol 1983; 96: 139–47.

    Google Scholar 

  8. Brubaker RF, Nagataki S, Bourne WN. Effect of chronically administered timolol on aqueous humor flow in patients with glaucoma. Ophthalmology 1982; 89: 280–87.

    Google Scholar 

  9. Brubaker RF, Nagataki S, Townsend N, Burn RR, Higgins RG. The effect of age on aqueous humor formation in man. Ophthalmology 1981; 88: 283–90.

    Google Scholar 

  10. Coakes RL, Brubaker RF. Method of measuring aqueous humor flow and corneal endothelial permeability using a fluorophotometry nomogram. Invest Ophthalmol Vis Sci 1979; 18: 288–93.

    Google Scholar 

  11. Greenidge KC et al. Acute intraocular pressure elevation after laser trabeculoplasty and iridectomy: a clinicopathologic study. Ophthalmic Surg 1984; 15: 105–10.

    Google Scholar 

  12. Johnson DH, Brubaker RF. Dynamics of aqueous humor in the syndrome of exfoliation with glaucoma. Am J Ophthalmol 1982; 93: 629–34.

    Google Scholar 

  13. Johnson DH, Liesegang TJ, Brubaker RF. Aqueous humor dynamics in Fuch's uveitis syndrome. Am J Ophthalmol 1983; 95: 783–90.

    Google Scholar 

  14. Nagataki S, Mishima S. Aqueous humor dynamics on glaucomato-cyclitic crisis. Invest Ophthalmol Vis Sci 1976; 15: 365–72.

    Google Scholar 

  15. Rodrigues MM, Spaeth GL, Donohoo P. Electron microscopy of argon laser therapy in phakic open angle glaucoma. Ophthalmology 1983; 89: 198–210.

    Google Scholar 

  16. Rosenblantt MA et al. Intraocular pressure rise after argon laser trabeculoplasty. Br J Ophthalmol 1987; 71: 772–5.

    Google Scholar 

  17. Schwartz AL, Whitten WE, Bleiman B. Argon laser trabecular surgery. Ophthalmology1981; 88: 203–12.

    Google Scholar 

  18. Spitznas M, Whitten WE, Bleiman B. The effect of laser trabeculoplasty on outflow facility and aqueous flow in primary open angle glaucoma. In: Kugler & Ghedini, editors. Ocular fluorophotometry and the future. Amsterdam, 1989.

  19. Thomas JV, Simmons RJ, Belcherr CD. Argon laser trabeculoplasty in the presurgical glaucoma patient. Ophthalmology 1982; 89: 187–97.

    Google Scholar 

  20. Van Buskirk EM et al. Argon laser trabeculoplasty. Studies of mechanism of action. Ophthalmology 1984; 91:1005–15.

    Google Scholar 

  21. Walker SD, Brubaker RF, Nagataki S. Hypotony and aqueous humor dynamics in myotonic dystrophy. Invest Ophthalmol Vis Sci 1982; 22: 744–50.

    Google Scholar 

  22. Weinreb RN et al. Immediate intraocular response to argon laser trabeculoplasty. Am J Ophthalmol 1983; 95: 279–86.

    Google Scholar 

  23. Wentworth WO, Brubaker R. Aqueous humor dynamics in a series of patients with third neuron Horner's syndrome. Am J Ophthalmol 1981; 92: 407–13.

    Google Scholar 

  24. Wilensky JT, Jampol LM. Laser therapy for open angle glaucoma. Ophthalmology 1981; 88: 213–17.

    Google Scholar 

  25. Wise JB, Witter J. Argon laser therapy for open angle glaucoma. Arch Ophthalmol 1979; 97: 319–25.

    Google Scholar 

  26. Yablonsky ME, Zimmerman TJ, Walman SR, Becker B. A fluorophotometric study of the effect of topical timolol on aqueous humor dynamics. Exp Eye Res 1978; 27/2:135–42.

    Google Scholar 

  27. Yablonsky ME, Cook DJ, Gray J. A fluorophotometric study of the effect of argon laser trabeculoplasty on aqueous humor dynamics. Am J Ophthalmol 1985; 99: 579–82.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Aliseda Pérez, D., Fernández Vila, P.C. & Beneyto Martin, P. Study on the aqueous humor flow measured by fluorophotometry after argon laser trabeculoplasty. Int Ophthalmol 16, 315–319 (1992). https://doi.org/10.1007/BF00917983

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00917983

Key words

Navigation