Abstract
α-Arylhydrazononitriles1 react with α-halogen carbonyl compounds in presence of K2CO3 to yield substituted4-amino-1-aryl-pyrazoles3. Pyrazolo[4,3-d]pyrimidines, pyrazolo[4,3-d]oxazinones and substituted 4-aminopyrazolecarboxylic acids can be obtained from3; the carboxyl group in the 5-position can be removed.
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Gewald, K., Calderon, O. 4-Amino-1-arylpyrazole durchThorpe-Cyclisierung. Monatshefte für Chemie 108, 611–616 (1977). https://doi.org/10.1007/BF00912807
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DOI: https://doi.org/10.1007/BF00912807