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Hydrazides of sarcolysine

  • Organic and Biological Chemistry
  • Published:
Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Conclusions

  1. 1.

    A series of N-acylsarcolysine hydrazides has been obtained by condensing N-acyl derivatives of sarcolysine with hydrazine hydrate in the presence of 1, 3-dicyclohexylcarbodiimide.

  2. 2.

    1-(Sarcolysyl)-2-p-[di-(s-chloroethyl)amino]phenacetylhydrazine was obtained by the reduction of 1-(N-carbobenzoxysarcolysyl)-2-p-[p-(2-chloroethyl)amino]phenacetylhydrazine.

  3. 3.

    1-(N-Formylsarcolysyl)-2-(p-[di-(2-chloroethyl)mino]benzylidene hydrazine and 1-(N-carbo-benzoxysarcolysyI)-2-p-[di-(2-chloroethyl)amino]benzylidene hydrazine were obtained by condensing N-acyl-sarcolysine hydrazides with p-[di-(2-chloroethyl)amino]benzaldehyde

  4. 4.

    l-(Sarcolysyl)-2-p-[di-(2-chloroethyl)amino]benzylidenehydrazine was obtained by condensing sarcolysine hydrazide with p-[di-(2-chloroethyl)amino]benzaldehyde.

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Literature cited

  1. L. F. Larionov and I. G. Spasskaya, Voprosy Onkologii,7, 1175 (1961).

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  2. I. L. Knunyants, O. V. Kil'disheva, and N. E.Golubeva, Izv. Akad. Nauk SSSR, Otd. Khim. Nauk, 1418 (1956).

  3. I. L. Knunyants, K. I. Karpavichus, and O. V. KiPdisheva, Izv. Akad. Nauk SSSR, Otd. Khim. Nauk, 1024 (1962).

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Authors and Affiliations

  1. Institute of Heteroorganic Compounds, Academy of Sciences of the USSR, USSR

    K. I. Karpavichus, S. V. Adomaitene, A. B. Paulyukonis, O. V. Kil'disheva & I. L. Knunyants

  2. Institute of Oncology, Ministry of Public Health Lithuanian SSR, USSR

    K. I. Karpavichus, S. V. Adomaitene, A. B. Paulyukonis, O. V. Kil'disheva & I. L. Knunyants

Authors
  1. K. I. Karpavichus
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  2. S. V. Adomaitene
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  3. A. B. Paulyukonis
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  4. O. V. Kil'disheva
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  5. I. L. Knunyants
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Additional information

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 4, pp. 874–876, April, 1968.

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Karpavichus, K.I., Adomaitene, S.V., Paulyukonis, A.B. et al. Hydrazides of sarcolysine. Russ Chem Bull 17, 835–837 (1968). https://doi.org/10.1007/BF00905764

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  • DOI: https://doi.org/10.1007/BF00905764

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