Conclusions
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1.
The kinetics of the intramolecular alkylation of 2-(9-iodononyl)-5-(carbethoxyacetyl)thiophene was studied in the presence of solid K2CO3.
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2.
The intramolecular alkylationof 2-(9-iodononyl)-5-(carbethoxyacetyl) thiophene is a first-order reaction with respect to 2-(9-iodononyl)-5-(carbethoxyacetyl) thiophene, with an activation energy of 9.7 kcal per mole.
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3.
On the basis of the principles found, it was hypothesized that the intramolecular alkylation of 2-(9-iodononyl)-5-(carbethoxyaeetyl) thiophene proceeds through a stage of formation of an anion fixed on the surface of K2CO3.
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 4, pp. 762–768, April, 1968.
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Taits, S.Z., Krasnyanskaya, É.A. & Gol'dfarb, Y.L. A new method of synthesizing macrocyclic compounds. Russ Chem Bull 17, 735–740 (1968). https://doi.org/10.1007/BF00905742
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DOI: https://doi.org/10.1007/BF00905742